2017
http://hdl.handle.net/10832/2565
2024-03-29T09:24:09Z
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Véralvadásgátló rágcsálóirtó szer okozta mérgezések 2010-2016 közti időszakban
http://hdl.handle.net/10832/2767
Véralvadásgátló rágcsálóirtó szer okozta mérgezések 2010-2016 közti időszakban
Fazekas, Béla; Orosz, Enikő; Bacsadi, Árpád; Erdélyi, Károly; Szeredi, Levente
SUMMARY
Background: Anticoagulant rodenticides are most commonly used for extermi nation of rodents in Hungary, so this type of poisoning often occurs.
Objectives: The aim of this survey was to describe the experiences of toxico logical studies of animal carcasses and other types of test samples received in
the laboratory from 2010 to 2016 with suspicion of poisoning with anticoagulant
rodenticide.
Materials and Methods: During the period under review, 112 animal subjects
were examined. In 32 cases, 4 types of 4-hydroxycoumarin derivatives (warfarin,
coumatetralyl, bromadiolone, brodifacoum) were detected by HPLC, and in 6
cases, the chlorophacinone of the indandione group was tested with GC-MS. In
addition to the examination of animal carcasses, 51 baits were analysed for the
presence of 4-hydroxycoumarin derivatives.
Results and Discussion: Traces of four different 4-hydroxycoumarin deriva tives (bromadiolone, brodifacoum, warfarin, coumatetralyl) and one indandione
derivative (chlorophacinone) were found in the organs of 38 carcasses (11 dogs, 3
cats, 1 goat, 1 wolf, 1 orangutan, 9 rabbits, 6 deer, 1 otter, 2 foxes, 1 hyena, 1 buz zard, 1 African sacred ibis). Mild to severe coagulation problems were observed in
the above cases indicative of anticoagulant rodenticide poisoning. Given the cir cumstances, these deaths were predominantly malicious poisonings, although
some of the cases may have been accidental. Among the poisonings 16 of them
were caused by bromadiolone, and 13 of them by brodifacoum, which is 76% of
the cases. Six different 4-hydroxycoumarin derivatives were detected (broma diolone, brodifacoum, difenacoum, fl ocoumafen, warfarin, coumatetralyl) in 41
baits of 51. Since the use of anticoagulant rodenticides is required in the defence
against rodents, poisoning of this type should also be expected in the future.
2017-12-01T00:00:00Z
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Nyúl eredetű Bordetella bronchiseptica törzsek virulencia faktorainak fenotípusos vizsgálata
http://hdl.handle.net/10832/2766
Nyúl eredetű Bordetella bronchiseptica törzsek virulencia faktorainak fenotípusos vizsgálata
Khayer, Bernadett; Görföl-Sulyok, Kinga Mária; Wehmann, Enikő; Szabó, Réka; Magyar, Tibor
SUMMARY
Background: Bordetella bronchiseptica is a widespread pathogen bacterium
causing various respiratory diseases in mammals. Little is known about the
background of infection of rabbits by B. bronchiseptica, although both asymp tomatic carriage and clinical manifestation of the disease generate economic
losses for breeders. Moreover, rabbits as companion animals imply zoonotic risk,
as well.
Objectives: In this work, the phases of infection by B. bronchiseptica strains
were investigated.
Materials and methods: 40 B. bronchiseptica strains, isolated between 1984
and 2011 from rabbits in Hungary and other countries, were used in this study.
The reach of the host was examined by motility assay under various circum stances (LB-37; LB-24; LB+MgSO4-37; LB+MgSO4-24). Adhesion was modelled by
haemagglutination using rabbit, cattle and sheep erythrocytes, and the produc tion of adenylate cyclase-haemolysin toxin was studied by haemolysis.
Results and Discussion: Most of the strains proved to be motile under all
examined circumstances, but the greatest motility zones were measured after
incubation at 37 °C on LB agar. Only one of the strains did not agglutinate any
of the four types of erythrocytes. Rabbit erythrocytes were agglutinated by
the highest number of strains. The lowest number of reactions were seen with
cattle erythrocytes. Haemolysis was strongest on Columbia agar supplemented
with 5% sheep blood. Supplementation with 5% horse blood resulted in weaker
haemolysis. Haemolytic activity was not consistent between different passages
of any strain.
Results have shown that there are no signifi cant differences between Hungarian
and foreign B. bronchiseptica strains. However, the behaviour and virulence of
the strains is considerably infl uenced by environmental parameters.
2017-12-01T00:00:00Z
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Staphylococcus aureus okozta folliculitis és furunculosis sertésben Esetismertetés és elkülönítő kórjelzés
http://hdl.handle.net/10832/2765
Staphylococcus aureus okozta folliculitis és furunculosis sertésben Esetismertetés és elkülönítő kórjelzés
Takács, Norbert; Pesír, Zoltán; Albert, Ervin; Kiss, Krisztián; Csuka, Edit; Biksi, Imre
Summary
Background: Dermal lesions in pigs are quite infrequent in comparison to com panion animals. Some pigs with unusual disseminated papular lesions have been
recently submitted to the Diagnostic Laboratory of the Department and Clinic for
Production Animals. During diagnostic workup, the authors have extracted some
further, previously unreported cases from their archives with similar dermal pat terns. These are used now to illustrate the differential diagnosis of Staphylococcus
aureus induced folliculitis and furunculosis.
Objectives: Two to three-week-old piglets in a high health status breeding herd
developed disseminated nodular dermal lesions. These were from a batch of pig lets weaned at 2 days of age, and reared artificially. Skin lesions were not associa ted with further clinical signs or with mortality, so the three weakest piglets were
sacrificed for diagnostic purposes. Other affected piglets recovered after cephalos porine therapy.
Materials and Methods: Dissection, histopathological examination of the skin
and major organs was performed, along with attempts to detect porcine circovirus 2
(PCV-2), porcine parvovirus (PPV) by polymerase chain reaction (PCR). Aerobic bacte riological examination of dermal lesions was performed. Carriage of methicillin-re sistance genes was assessed also with PCR.
Results and Discussion: Diagnostic examination of the skin revealed up to 5 mm
diameter raised nodules, some with central ulceration. All other organs were free of
alterations. Typical nodules were follicles distended with neutrophil granulocytes, in
some of the nodules inflammation involved also the follicular wall and the surround ing dermis. Cocci were seen scattered in inflammatory infiltrates. Aerobic bacterio logical examination of dermal lesions revealed Staphylococcus aureus in pure culture.
None of the detected strains harboured mecA/mecC gene.
Folliculitis and furunculosis caused by Staphylococcus aureus is quite rare in pigs, but
occurs with some frequency in other domestic species. Differential diagnostics of dis seminated nodular dermal lesions in pigs include swine pox, chronic exudative der matitis, hypersensitivity form of mange, granulomatous dermatitis, and demodicosis.
2017-12-01T00:00:00Z
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Szarvasmarhák neosporosisának előfordulása és vetélésekben betöltött szerepe a Kárpát-medence térségében
http://hdl.handle.net/10832/2764
Szarvasmarhák neosporosisának előfordulása és vetélésekben betöltött szerepe a Kárpát-medence térségében
Sáfár, János; Antós-Nizsalóczki, Magda; Bajcsy, Árpád Csaba
SUMMARY
Background: The authors summarized the results of studies from the region
of the Carpathian Basin, which deal with a protozoan parasite, Neospora caninum
(Apicomplexa: Sarcocystidae) being responsible for a signifi cant percentage of
infectious abortions in cattle. Affected cows typically abort during the mid-term
of gestation. The most typical histopathological fi ndings in aborted foetuses are
multifocal encephalitis and infl ammatory lesions in other organs. Nevertheless,
in most cases, the new-born calf will be a clinically healthy carrier, which con tributes to the maintenance of neosporosis in the herd.
Objectives: The aim was to summarize available serological data of bovine
neosporosis and its role in abortions in the region of the Carpathian Basin.
Materials and Methods: The authors reviewed reports from the region of
the Carpathian Basin that describe the prevalence of N. caninum and its role
in bovine abortions, and compared the seroprevalences of different countries.
Results and Discussion: Neospora caninum is widespread in the world, and
it occurs in the region of the Carpathian Basin, as well. Although its seropreva lence shows variation in the different countries, it is usually high, and it is higher
in aborted cattle, than in cattle where abortion did not occur. Nevertheless, the
rate of seropositivity is higher among older animals and in off-springs of sero positive cattle, supporting the fact that both vertical and horizontal routes of
infections are signifi cant. In the latter case, dogs (defi nitive hosts) kept together
with cattle may play a crucial role. Seropositivity in hunting dogs and cows that
live together with shepherd dogs was higher. On the other hand, breed, herd
size and sometimes even age do not seem to have any signifi cant infl uence
on seroprevalence, however, this may differ among various husbandry systems.
Currently, a specifi c treatment for neosporosis does not exist, neither are com mercial vaccines available in this region, therefore, improvement of hygienic
conditions is the only effective way to prevent signifi cant economic losses
caused by N. caninum.
2017-12-01T00:00:00Z
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Nyári meleg okozta hőstressz hatásának vizsgálata a tejelő szarvasmarha szaporodásbiológiai mutatóira
http://hdl.handle.net/10832/2763
Nyári meleg okozta hőstressz hatásának vizsgálata a tejelő szarvasmarha szaporodásbiológiai mutatóira
Novotniné Dankó, Gabriella; Rónai, Ákos; Tóth, Péter Pál; Szabó, Dávid; Balogh, Péter; Kovácsné Koncz, Nóra
SUMMARY
Background: The Hungarian climate has continental character, the average
temperature is 10 to 11 °C and the annual average temperature is in line with
global trends. The warmest period of the year is the end of July and the begin ning of August. According to the data of the National Meteorological Service year
2015 was signifi cantly warmer than usual.
Objectives: Heat stress is a major contributing factor to the low fertility of dairy
cows inseminated in the late summer months.
Materials and methods: We examined the reproductive performances of cows
and heifers on Holstein-Friesian farms, with particular regard on hot summer
months. We focused mostly on the year 2015, which was the warmest globally
since 1850.
Results and discussion: Based on our results the conception rate of lactating
cows in summer months was poor. However the fertility index of the heifers
was equally good throughout the year (between 1.6-2.5), the cow’s fertility index
increased from May, and the worst was in August (8.8). Examining the effect of
heat stress on gestation length we observed that parallel with the monthly aver age temperature rising, calving began earlier. In summer period the calving may
start even on day 273 of gestation. There were up to 13 more day differences in
gestation length between the winter and summer calving animals. The calving
interval can be 450 days of animals which service period is in the hottest sum mer time, because of the poor fertility. Our results demonstrated in the hottest
months of the year that the conception rate was very low. Therefore, we suggest
not to do the insemination process routinely, but paying particular attention
on physiological condition and age of the animals, on weather (temperature,
front-effects), and so on. Insofar the circumstances are inadequate we may
decide to postpone the insemination, not to waste time, money and energy.
2017-12-01T00:00:00Z
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Az ellés körüli időszak ellenőrzésének jelentősége tejelő tehenészetekben Irodalmi összefoglaló
http://hdl.handle.net/10832/2762
Az ellés körüli időszak ellenőrzésének jelentősége tejelő tehenészetekben Irodalmi összefoglaló
Szenci, Ottó; Szelényi, Zoltán; Lénárt, Lea; Buják, Dávid; Kézér, Fruzsina Luca; Han, Bo; Horváth, András
SUMMARY
The authors in this literature review emphasize that parallel with the successful
genetic selection for higher milk production in Holstein dairy cows, a dramatic
decline in their reproductive performance has occurred. The average number
of days open, the number of services per conception and the number of cows
culled for infertility increased substantially. At the same time, it is very impor tant to emphasize that reproductive performance of heifers was not affected.
In order to decrease prolonged lactations and the number of cows culled for
reproductive reasons it is very important to improve our reproductive monitor ing practices. Achievement of optimum herd reproductive performance (calving
interval of 12 or 13 months with the fi rst calf born at 24 months of age) requires
high-level management activities, especially during the fi rst 100 days follow ing calving. After calving, a cow overcomes a series of physiological hurdles
before becoming pregnant. Several real-time diagnostic devices and methods
are available to monitor specifi c events in the peripartal and service period to
appropriately identify problems and their potential causes furthering their rec tifi cation. These include calving alarm vaginal thermometers, monitoring rumi nation, electronic hand-held BHBA measuring systems, metabolic profi le tests,
regular measurements of milk constituents, long-term measurement of retic uloruminal pH value by indwelling and wireless data transmitting units, ultra sonography, oestrus detectors and/or detection aids and on-farm progester one tests. According to the authors the following monitoring and management
activities are needed to pursue during the early postpartum period to reach the
optimal calving interval: prediction the onset of calving, monitoring post par turient metabolic diseases, early diagnosis of post parturient uterine diseases,
accurate oestrus detection, correct timing of insemination and accurate early
pregnancy diagnosis.
Despite the higher milk production acceptable fertility results even in large scale dairy farms can be achieved if the impact of the above-mentioned factors
causing decreased fertility can be moderated.
2017-12-01T00:00:00Z
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Statisztikai ellenőrző diagramok az állatitermék-előállításban
http://hdl.handle.net/10832/2761
Statisztikai ellenőrző diagramok az állatitermék-előállításban
Nagy, Sára Ágnes; Tőzsér, Dóra; Szombath, Gergely; Baranyi, Dániel; Reibling, Tamás; Biksi, Imre; Solymosi, Norbert
SUMMARY
Background: In our age, the information society, the computer based technol ogies, including the data analytical procedures are part of each sites of the life.
In the production animal sector more and more data are generated day by day.
Unfortunately, only a small piece of this huge amount of data is transformed to
information, that can be interpreted, used by professionals in decisions.
Objectives: The present work demonstrates a relatively simple statistical
approach that may help to improve the production, animal health and welfare
measures in animal production sector.
Materials and methods: Since the 1920s in the industry sector the Statistical
Process Control (SPC) is a widely used toolbox to help the producers to improve
the efficiency and profitability of production processes. The components of the
SPC toolbox are the „magnificent seven”: histogram, check sheet, pareto chart,
cause-and-effect diagram, defect concentration diagram, scatter diagram, con trol chart. The last one (also called as Shewhart chart) is the most widely used
tool of SPC. Through a case study on piglet weaning weight the authors summa rizes the most important momentums of the creation and interpretation of the
control charts. In the example a real world based simulated dataset was used to
construct the control charts. Beside this a short review is presented to demon strate control chart applications in animal production areas.
Results and Discussion: The presented case study helps the reader to under stand how the statistical control charts can improve the surveillance of animal
production and animal health. The authors emphasise that in the „big data”
age it is necessary to develop the computational, data analytical skills of veter inarians working on farms, to be able to convert the accumulating raw data to
professionally usable information.
2017-11-01T00:00:00Z
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A nyers juh- és kecsketej minőségét befolyásoló főbb tényezők
http://hdl.handle.net/10832/2760
A nyers juh- és kecsketej minőségét befolyásoló főbb tényezők
Székelyhidi, Rita
SUMMARY
Based on large number of publications in scientific literature, the author provide
information on the factors affecting the quality of raw sheep and goat milk. She
presents the effect of the variety within species, the impact of stage of lacta tion and seasons, the influence of milking and changes in somatic cell count in
milk composition. In sheep milk the amount of milk fat, milk protein and casein
in the final stage of the lactation rises compared to the first stage. In goat
milk the concentration of milk fat decreases in the middle stage of lactation
compared to the first stage and it increases in the final stage and the amount
of milk protein and casein constantly increases during the lactation. High milk
yield is usually combined with a long lactation period, normally 8-10 months,
but the dairy sheep maintain lactation for 2 years without more calving. A high
somatic cell count milk have a higher proteolytic activity, and they contain larger
quantities of fat and casein and lower concentration of whey proteins, especially
serum albumin and immunoglobulin. The proteolytic enzymes in the somatic
cells attack the αs2- and β-casein. Just like the goats, the sheep also respond to
changes in the environment, they have developed a genetic multiplication pace
that follows the seasons change and the better food endowments. If the lacta tion period begins before the spring or the rainy season, lactation period will be
longer because of the better feed. There is 80-90% correspondence between
the udder size and the milk yield, and the milk yield depends on the surface size
of alveoli, too. Increasing the number of milking ordinarily increases the amount
of the expressed milk, but in this case there are significant differences between
individual animals.
2017-11-01T00:00:00Z
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Okkult Dirofilaria immitis szívférgesség kutyában Esetismertetés és irodalmi áttekintés
http://hdl.handle.net/10832/2759
Okkult Dirofilaria immitis szívférgesség kutyában Esetismertetés és irodalmi áttekintés
Vörös, Károly; Becker, Zsolt; Arany-Tóth, Attila; Gyurkovszky, Mónika; Farkas, Róbert
SUMMARY
Background: Occult dirofilariosis caused by Dirofilaria immitis occurs in dogs when
no microphilariae can be detected in the peripheral blood, despite the presence of
adult heartworms.
Objectives: The authors report on an autochthon case of true occult dirofilari osis caused by D. immitis in a dog originated from an endemic region of Hungary.
A comprehensive review of the literature of occult dirofilariosis was added to the
case report.
Materials and methods: No macrocyclic lactone treatment/prevention was
applied as to the history of the patient. The diagnosis was based on the clinical
symptoms, radiologic alterations of the lungs as well as on the echocardiographic
findings. Heartworm disease (HWD) was confirmed by four positive antigen tests
of different manufacturers.
Results and discussion: The patient was categorized into the severe, third clini cal stage of HWD. Major clinical symptoms included occasional fainting, weakness,
frequent coughing, severe dyspnoea, and signs of right-heart failure. Radiographic
and echocardiographic alterations were characteristic for advanced HWD. Echo cardiography also revealed secondary pulmonary hypertension and a few adult
worms were detected within the right major pulmonary artery. The dog was stabi lized by treating the congestive heart failure for three weeks. Thereafter, complex
HWD treatment procedure was applied as to the recommendations of the latest
(2014) version of the American Heartworm Society. Remarkable improvement of
the clinical symptoms as well as radiographic and echocardiographic alterations
were seen after one month following HWD treatment. By six months, the dog
nearly completely healed clinically and the antigen tests became negative.
True occult dirofilariosis should be considered when no microphilariae are present
in the peripheral blood without preceding macrocyclic lactone application and
adult heartworms can be detected by antigen tests and/or with echocardiogra phy. This phenomenon can cause a diagnostic challenge and should be especially
considered in endemic regions of heartworm disease.
2017-11-01T00:00:00Z
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Juvenilis, aorta típusú spirocercosis esete kutyában Klinikopatológiai esettanulmány
http://hdl.handle.net/10832/2758
Juvenilis, aorta típusú spirocercosis esete kutyában Klinikopatológiai esettanulmány
Tóth, Tivadar; Regős, Anikó; Balka, Gyula; Jakab, Csaba
SUMMARY
Background: Spirocerca lupi is a spirurid nematode of carnivores, particularly
Canidae, of worldwide distribution.
Objectives: The aim of the present clinicopathological study was to describe
pathological, and histopathological characteristics of the aortic type spirocercosis
in a young dog, which died suddenly during the clinical examination, without
correct clinical diagnosis.
Materials and Methods: Aortic wall and lung samples were separated
and conserved in buffered, 8% formalin for 24 hours at room temperature,
embedded in paraffin wax and further processed for sectioning (3–4 µm). During
the histopathological investigation hematoxylin and eosin, Azan- and Perls stainings, and inflammatory-, necrosis-, haemorrhage-, collagen fibre-, fibroblast
cell-scoring systems were used.
Results and Discussion: In a routine post-mortem examination, paler than
normal visible mucosal membranes (hallmark of the acute posthaemorrhagic
shock), large quantity of blood (~250 ml) were found in the thoracic cavity, and in
the periaortal, furthermore precardial mediastinal tissues. 14–15 non-neoplastic,
Spirocerca lupi-induced inflammatory nodules, and 5 mm in length transmural
rupture were detected in the wall of the aorta.
This report details the possible cause of the sudden death in a dogs, due to fatal
aortic rupture as a result of Spirocerca lupi infection.
2017-11-01T00:00:00Z
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Sertések légzőszervi megbetegedéseinek elkülönítő kórjelzése II. A növendék malacok megbetegedései
http://hdl.handle.net/10832/2757
Sertések légzőszervi megbetegedéseinek elkülönítő kórjelzése II. A növendék malacok megbetegedései
Orosz, Adél; Selmeci, Csaba; Takács, Norbert; Kiss, Krisztián; Albert, Ervin; Biksi, Imre
Summary
The authors describe the pathogenesis and differential diagnosis of important
porcine respiratory diseases, based on the available literature and on their prac tical experiences. Aiming to help clinicians to identify respiratory conditions pos sibly „on the spot”, different diseases are discussed according to the production
phase they likely to occur in, and also according to the elicited clinical signs. In
the second part of this multi volume article, respiratory diseases in the growing
period are detailed. Readers are encouraged to consult the first volume of this
series as basic information on clinical signs, pathological lesions, sampling and
diagnostics of certain respiratory conditions are not repeated here for the sake of
conciseness.
Clinical examination of grower age groups is the first step to diagnosis. The ani mals’ response to environmental stimuli should be assessed. Important to note,
whether the respiratory signs are present in all age groups, or only observed in
certain batches (e. g. epidemic swine influenza versus Mycoplasma hyorhinis
infection). Common lesions in animals affected with respiratory signs include
bronchopneumonia, interstitial pneumonia etc. Ear tip necrosis related embolic
pneumonia, and polyserositis due to either one or more of Haemophilus para suis, Mycoplasma hyorhinis or Streptococcus suis are common findings in growers,
being usually less frequent in suckling piglets or fatteners. One should not skip
examination of non-respiratory organs (spleen, intestines etc.) as they might
have important clues to diagnosis. Serological “profiling” as part of supplemen tary examinations has a limited role in the grower phase: depletion of colostral
antibodies can be detected in case of most pathogens but seroconversion to
them would occur usually later, in the finishing phase. However, early serocon version to e. g. Mycoplasma hyopneumoniae would indicate an important devia tion from “usual” and would be an asset to diagnosis. Classical respiratory prob lems like PRRS, swine influenza, Glässer’s disease and less studied syndromes
as Acute Respiratory Distress Syndrome, ear tip necrosis related embolic pneu monia and Pneumocystis carinii infection are discussed in details.
2017-11-01T00:00:00Z
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IV. Országos Állatorvos-Agrár Sportnap és Családi Hétvége
http://hdl.handle.net/10832/2756
IV. Országos Állatorvos-Agrár Sportnap és Családi Hétvége
Bándy, Pál
2017-11-01T00:00:00Z
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A 3 hetes csoportos fiaztatási rendszernek – mint a PRRS mentesítés egyik elemének – termelési tapasztalatai Esettanulmány
http://hdl.handle.net/10832/2755
A 3 hetes csoportos fiaztatási rendszernek – mint a PRRS mentesítés egyik elemének – termelési tapasztalatai Esettanulmány
Búza, László; Pogácsás, Imre; Ózsvári, László
Summary
Background and Objectives: Many commercial swine farms cannot implement
all-in-all-out (AIAO) because of different capacities of farrowing, nursery and finishing units.
However, breaking the infection cycle is essential in disease eradications, thus creation of
a sustainable batch management system (BMS) gives an opportunity to implement AIAO.
This study surveyed production impact of a 3 weeks BMS implementation as an element
of a PRRS Eradication Plan (PEP).
Materials and Methods: The farrow-to-finish Topigs genetics swine farm had 800 sows
and their progeny. The farm was obliged to set up PEP following initiation of a mandatory
national PRRS eradication program. Due to the different capacities of consecutive farm
production units, a 3 weeks BMS was launched with oestrus synchronization for grouping
sows starting in August 2015. The farm production indices were surveyed from August 2014
to July 2016 (one year before and after BMS launch) to measure its impact. The data were
processed with Microsoft Excel© program.
Results: After launching BMS monthly farrowing (F) decreased by 10%, artificial insemina tion (AI) by 11%, but AI/F increased by 2% with an extra 0.4 live piglets/litter. Although litters/
sow/year and weaned piglets/sow/year indices slightly decreased, the number of slaughter
pigs/sow/year increased by 1.37. Mortality and culling rate were improved; in the farrowing
unit the combined index decreased from 9.6% to 6.5%; in the nursery from 6.9% to 1.6%,
and for finishers from 10.5% to 7.5%. Feed conversion ratio has improved in the nursery
from 2.27 to 2.17 and for finishers from 4.33 to 3.88. Total drug cost per slaughter pig decrea sed by 23.8% (form €12.4 to €9.5), of which antibiotics by 38.4% and vaccination by 22.0%,
contrary to an increased cost of disinfections by 150.9%.
Discussion and Conclusions: The results support that a 3 weeks BMS as element of
PEP is an inevitable tool for the implementation of AIAO. BMS helps to break the PRRSV
infection cycle, thus, accelerates PRRS eradication and improves swine production indices.
2017-11-01T00:00:00Z
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A vadászható fajok védelme: az orvvadászat bizonyíthatósága az igazságügyi genetika segítségével Eseti alkalmazások
http://hdl.handle.net/10832/2754
A vadászható fajok védelme: az orvvadászat bizonyíthatósága az igazságügyi genetika segítségével Eseti alkalmazások
Zenke, Petra; Egyed, Balázs; Pádár, Zsolt
SUMMARY
Background: Recently, wildlife poaching as a part of wildlife crime caused a
serious decline for several species. Integration of novel methods or specific
applications into forensic sciences increases the range of available actions
against these global activities.
Objectives: The goal of our paper is to present some recent challenges and
limitations of Hungarian wildlife forensics, call attention to these problems, and
increase the veterinary profession’s interest in wildlife crime investigation.
Materials and Methods: In our presented cases several types of samples
– meals (muscles), hairs, swabs, different evidence materials (handkerchief
papers, textiles, hunting tools, secondary surfaces, transferred materials) – were
examined by DNA analyses after (morphological) selection. The targets of our
PCR-based methods are located in both nuclear and mitochondrial genome.
The species identification was carried out by multiplex analyses of mtDNA Cyto chrome (b) region. Additionally, as requested by authorities for the different level
of individualisation, the red deer-specific nuDNA STRs (10 loci in two 5-plex) or
mtDNA control region – of Sus scrofa (CR 15435-16680) and Cervus elaphus (CR
15442-16357) – were genotyped, or sequenced.
Results and Discussion: The professional experiences and the legal conse quences of presented caseworks reveal the usefulness of forensic genetics in
solving Hungarian wildlife crimes. Where persons are skilled in this discipline,
the genetic evidence can play an important role in police investigation as well
as in the legal process.
2017-10-01T00:00:00Z
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Egyszeri adagolású szeknidazolkezelés hatékonysága Giardia duodenalis fertőzés esetén kutyákban
http://hdl.handle.net/10832/2753
Egyszeri adagolású szeknidazolkezelés hatékonysága Giardia duodenalis fertőzés esetén kutyákban
Ceren, Karahalli; Kerem, Ural
SUMMARY
Objectives: The purpose of this study was to determine whether secnidazole
administered at a single dose of 30 mg/kg, orally, decreases or eliminates Giar dia cyst shedding, and to validate the benefit of secnidazole treatment on clini cal signs and faecal scoring in dogs naturally infected with Giardia duodenalis.
Materials and Methods: A total of 12 dogs, from various breed, age and of
both sexes were involved. The diagnosis was based on the detection of tropho zoites and/or cysts via faecal flotation among dogs naturally infected with Giar dia sp., and also by use of rapid diagnostic test kits. Cyst count per gram faeces
(days 0., 3., 7. and 10) and faecal scores were analyzed among groups. Two groups
of dogs, the secnidazole group (n:6) and the control group (n:6) were enrolled. In
dogs involved in treatment group secnidazole was administered at a single dos age of 30 mg/kg orally on day 0, whereas control group received placebo.
Results: On days 3., 7., and 10. there was significant (P<0.01) reduction in cyst
shedding; whereas evaluation of mean geometric cyst shedding revealed 100%
reduction. Evaluation of faecal scores on daily basis revealed that feces of dogs
in treatment group after day 3 were appearently close to normal score as 3.
Conclusion: As a result of this study, secnidazole at a single dose might be
practically applicable, reasonably priced, safe, and effective drug for therapy of
dogs with giardiasis.
2017-10-01T00:00:00Z
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A mágneses rezonanciás képalkotás (MRI) diagnosztikai és differenciál diagnosztikai szerepe epilepsziás kutyák kivizsgálásában
http://hdl.handle.net/10832/2752
A mágneses rezonanciás képalkotás (MRI) diagnosztikai és differenciál diagnosztikai szerepe epilepsziás kutyák kivizsgálásában
Lőrincz, Borbála Aranka; Agustina, Anson; Bajzik, Gábor; Csébi, Péter; Alexander, Tichy; Garamvölgyi, Rita
SUMMARY
Background: Epilepsy is one of the most common neurologic disorders in dogs,
presenting a prevalence up to 5,7 % in the canine population. The most impor tant factor in prognosis and therapy is the differentiation of primary, cryptogenic
and secondary epilepsy, which is possible with magnetic resonance imaging
(MRI) in most of the cases.
Objectives: The aim of the present study was to determine the prevalence of
primary and secondary epilepsy in dogs, and to find out the underlying causes of
secondary epilepsy based on MRI findings. Furthermore, to evaluate the differ ences in lateral ventricle asymmetry and ventricular enlargement between the
epileptic dogs and a control group of dogs.
Materials and Methods: MRI of 83 epileptic dogs (31 females and 52 males;
aged between 0.3–14 years, weighing between 1.8–72 kg) and 31 control dogs (7
females and 24 males; aged between 1–14 years, weighing between 3–42 kg)
was performed with a 1.5T MR scanner. The imaging protocol included the fol lowing sequences: T2w in transversal, sagittal and paradorsal planes, FLAIR in
transversal plane, thin sliced T1w 3D in sagittal plane followed by transversal and
paradorsal reconstructions, and ToF angiography in transversal plane. Intrave nous contrast medium was applied in cases with structural lesions.
Results and Discussion: Sixty three dogs (76%) showed no abnormalities in
the MRI, and were classified as primary epilepsy. Twenty dogs (24%) showed
structural brain lesions. In those cases the final MR diagnosis was intracranial
neoplasia (n = 10), encephalitis and Chiari malformation (n = 4), porencephaly and
hydrocephalus (n = 1). Asymmetry of the lateral ventricles was present in 11% in
the primary epileptic group, 40% in the secondary epileptic group and 25% in
the control group. Ventriculomegaly was mildly overrepresented in the epileptic
group and showed a high prevalence in brachycephalic dogs independently from
clinical subgroup. According to our findings lateral ventricle asymmetry and ven triculomegaly are most likely not epileptogenic phenomena.
2017-10-01T00:00:00Z
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Kutyák heredaganatainak incidencia-, valamint E-cadherin alapú immunhisztokémiai vizsgálata Onkopatológiai tanulmány
http://hdl.handle.net/10832/2751
Kutyák heredaganatainak incidencia-, valamint E-cadherin alapú immunhisztokémiai vizsgálata Onkopatológiai tanulmány
Jakab, Csaba; Szilágyi, Máté
SUMMARY
Background: The major types of testicular tumour in dogs are sex-cord stromal
tumours, germ cell tumours, and mixed type of the germ cell-, and sex-cord
stromal tumours.
Objectives: The first goal of the present study was to describe the canine testi cular tumour incidence in Hungary, based on the histopathological investigation
of the biopsy samples at the Department of Pathology. The second aim of the
present work was about the E-cadherin based immunhistochemical differentia tion between Leydig- and Sertoli cell tumours.
Materials and Methods: Testicle tumour samples were separated and con served in buffered, 8% formalin for 24 hours at room temperature, embedded
in paraffin wax and further processed for sectioning (3-4 µm) and immunohis tochemistry (antibody: anti-E-cadherine, rabbit, polyclonal, dilution: 1:100). The
number of the biopsy samples was 147.
Results and Discussion: The peak rate of testicular tumours was between
the age of 9 and 12 years as well as the most emphasized breeds in connec tion with testicular tumours were the German shepherd dogs, Yorkshire terriers,
poodles and mixed breed dogs. The most frequently diagnosed tumour proved
to be the seminomas (53,06%), followed in order by the Leydig-cell tumours
(40,14%) and Sertoli-cell tumours (14,28%). Solid Leydigomas were negative for
E-cadherine, and solid Sertolimas showed intense, linear, membranous E-cad herine-positivity. We detected similar result during the E-cadherine-based
immunhistochemical investigation of the lipidisated, vaculisated Leydigomas,
and lipidisated (steroidogenic) Sertoliomas.
2017-10-01T00:00:00Z
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Embriófelszívódást okozó granulosasejtes petefészek-daganat kancában Esetismertetés
http://hdl.handle.net/10832/2742
Embriófelszívódást okozó granulosasejtes petefészek-daganat kancában Esetismertetés
Vincze, Boglárka; Kútvölgyi, Gabriella; Machay, Krisztina; Jakab, Csaba; Szenci, Ottó; Baska, Ferenc
SUMMARY
Background: Granulosa cell type tumours are the most common tumour in the
equine ovary. They are usually benign and unilateral. They are often associated
with the cessation of the normal oestrous cycle in mares and the suppression
of the normal remaining ovary. Clinical diagnosis of this condition is based on
hormone tests (inhibin, testosterone, progesterone) but suspected diagnosis can
be made based on physical examination (rectal palpation, ultrasonography, dis section).
Objectives: The aim of this study was to summarize the present knowledge
about granulosa cell type (GCT) tumours in mares and to present an atypical
case from the practice.
Materials and methods: A 22-year-old Holstein broodmare has been pre sented with previous pregnancy loss in the history. Therefore a specialized
reproductive examination has been performed (physical examination, rectal and
ultrasonographic examination, hormone analysis, endometrium biopsy). Based
on the owner’s decision, the mare was euthanized and the left ovary has been
fixed in buffered formalin solution and histological examination has been made.
Results and discussion: Based on all information available, the diagnosis of
granulosa cell type tumour has been made. Interestingly, the contralateral ovary
was not affected, because the mare could have been pregnant and there were
active ovarian structures (follicles and corpora lutea) on the right ovary during
the last breeding season. The authors could conclude that in case of GCTs, a
thorough reproductive examination in needed for the diagnosis, but in case of
this condition, the contralateral ovary is not always affected and mares some times are able to conceiv
2017-10-01T00:00:00Z
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A hazai lovas állatorvosi praxisok menedzselésének jellemzői
http://hdl.handle.net/10832/2740
A hazai lovas állatorvosi praxisok menedzselésének jellemzői
Baranyi, István; Ózsvári, László
SUMMARY
Background: The number of horses in Hungary is relatively low compared to
the Western-European countries. Hence, in parallel with the improving eco nomic conditions there is a great opportunity for the Hungarian equine sector
to largely develop in a short period of time, which would increase the demand
for the equine veterinary services.
Objectives: The aim of our study was to survey several management param eters of the Hungarian equine veterinary practices about their relationships with
horse owners and other equine veterinarians, their income, profit and future
development possibilities.
Materials and Methods: The survey was conducted between December 2015
and March 2016 with an Internet-based questionnaire having 41 questions and
aiming at equine practitioners directly. Altogether 56 vets filled the question naire completely from every region of Hungary.
Results: The findings show that the relationship with other vets is sometimes
hostile because of the harsh competition. In the horse owner-veterinarian rela tionship the communication is very often not effective. The horse owners' pro pensity to pay is generally low, so is the vets' application of the obligation to
issue invoices. The average mark-up of the equine services is 54.7% and the
monthly income follows a seasonal pattern (the lowest income in December and
January). The equine vets' expectations on the number of horses and character istics of horse owners are positive at large and they expect the number of group
vet practices to grow.
Discussion and Conclusions: The income and profitableness of the Hungarian
equine practices is moderate on average which would largely be improved if the
horse owners received the veterinary medicinal products by the vets only, the
mark-up rate was enhanced and legal contracts with horse owners and riding
halls became more common.
2017-10-01T00:00:00Z
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Tengeri és édesvízi biotoxinok élel miszer-toxikológiai jelentősége. II. Halak és halászati termékek Irodalmi összefoglaló
http://hdl.handle.net/10832/2731
Tengeri és édesvízi biotoxinok élel miszer-toxikológiai jelentősége. II. Halak és halászati termékek Irodalmi összefoglaló
Lehel, József; Lányi, Katalin; Laczay, Péter
SUMMARY
The authors summarise the chemical, toxicokinetic, toxicological and clinical
properties and characteristics of biotoxins (ciguatoxins, tetrodotoxin) and bio genic amines (histamine) found in marine and freshwater fish. Biotoxins pro duced by different dinoflagellates can also be found in the body of fish and can
be taken up by nutrition. However, certain fish species produce toxins that are
stored in their organs and tissues. Generally, these toxins are heat-stable and
resistant to gastric juice.
Ciguatoxins are lipid soluble and distributed in the whole body of fish. Basically,
they bind to the voltage-dependent sodium channel causing depolarisation of
the membrane due to sodium influx. Consequently, they increase the influx of
calcium and water into the cell leading to muscle contraction, release of neu rotransmitters, decrease of nerve stimulation and paralysis. Characteristic signs
of the toxicosis are paraesthesia, nervous system signs, gastro-intestinal prob lems, and rarely cardiovascular alterations.
Tetrodotoxins are particularly concentrated in the offal of fish (liver, ovary, intes tines) and the skin with lesser extent. They are potent neurotoxins and block
the voltage-gated sodium channel and therefore the influx of sodium, however,
having no effect on potassium ions.
The symptoms of intoxication include numbness at orofacial area, paraesthesia,
gastro-intestinal signs, incoordination, unable to move and general paralysis.
The freshwater biotoxins produced by blue algae do not accumulate in different
vectors. They act rather by direct contact with the human body and have differ ent biological effects (e.g. hepatotoxic, neurotoxic).
Scombrotoxin (histamine) is a biogenic amine with potent biological action that
is produced during the normal metabolism of fish or due to microbial decarbox ylation. It may be present in large quantities in fishery products which may be
harmful but not fatal to the consumers.
The legal official regulations which are important from the aspect of consumer’s
health care are also reviewed.
2017-09-01T00:00:00Z