Currently used antiprotozoal drugs in domestic animals

Abstract

Many determinantal and significant animal diseases are caused by different protozoan species, and in order to combat these diseases antiprotozoal drugs are applied. The infections caused by protozoa can cause huge economic and health impacts. The drugs that are currently available for treatment are becoming less effective due to drug resistances. This is a consequence of protozoal species evolution, adaptation and protozoal cross resistances. Despite this, there remains a lacking effort for the development of novel antiprotozoal drugs with altered mechanism of actions. For numerous protozoal diseases, the drugs assigned are toxic and initiate harmful side effects.