Ultra short pain effect during ovariectomy

Abstract

In order to measure ultrashort pain effects during a surgery, 34 female dogs undergo OVE procedure, which consider causing a moderate level of pain. In our research, we focused on the stress system composed of the nervous, endocrine and circulatory system and its response to the surgery by measuring the cortisol and insulin level at four time point during the OVE. Two types of anesthetic drugs combinations have been used in our research to compare their effect on the stress response during the procedure; xylazine, ketamine and diazepam combination, and fentanyl, ketamine, midazolam and propofol combination. Moreover, additionally to our research group, a control group operated by expert surgeon was used to discover the effects of time and experience of the operators on our results.