Genetics and phenotypes of Chondrodysplasia (Achondroplasia) across domestic animal species

Abstract

This diploma work is dedicated to the condition of disproportionate dwarfism in animals called chondrodysplasia, the genetics behind it and the phenotypic appearance of the animals suffering from it. I have shortly described several domestic animal species separately, what the characteristics are and, if known, the genetic mutation causing it. Focus has been put on the comparison between the species and also between breeds within a species. The phenotypes generally show similarities while the gene mutations differ between and within species. In many of the cases the etiology behind the gene mutation seems to be still unclear.