Porcine Respiratory Disease Complex and the involved pathogens

Abstract

Porcine respiratory disease complex (PRDC) is a multifactorial disease that significantly impacts global swine production, causing substantial economic losses. It involves a variety of infectious agents, including viruses, bacteria, and parasites, along with non-infectious factors such as environmental stressors, genetics, and herd management practices. This thesis provides an in-depth exploration of the primary pathogens responsible for PRDC, focusing on viral agents such as porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus 2 (PCV2), and influenza-A virus (IAV), as well as bacterial agents including Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Glaesserella parasuis, Bordetella bronchiseptica, Pasteurella multocida, and Streptococcus suis.