Újdonságok az állatorvosi epilepsziában - 2023 : Irodalmi összefoglaló

Abstract

In this „annual mini-review” the most relevant research results in the field of clinical epilepsy in dogs and cats will be described. The author selected and summarised from 2023 several useful findings from the international literature including own works. The following important topics will be presented. Autoimmune encephalitis was described in cats. The first case series has been published ten years ago, but now more detailed description with more cases were published. It seems that the inflammation affects the temporal lobe. Most cats showed acute temporal lobe seizures with orofacial automatism, hypersalivation, facial twiching, gagging. The brain MRI and the CSF analysis were frequently unremarkable but the antibodies against LGI1 (leucine-rich gliome-inactivated 1) was detectable in all cats. Another study showed, that for the treatment of epileptic cats the phenobarbital can be used as once a day therapy, which may be easier for many owners than the usual twice daily treatment. In another study the haematologal findings were systematically evaluated in cats undergoing phenobarbital therapy. The majority of cats showed neutropenia or other cytopenias, but these changes were usually mild and clinically not relevant. An interesting case report showed how to treat succesfully acute phenobarbital induced liver failure in a dog. Furthermore a consensus statment was published about status epilepticus therapy in dogs and cats. Feline hypertensive encephalopathya and its outcome was evaluated and published. The author hopes that his work could facilitate research implementation into the daily practice and published knowledge from 2023 can be directly beneficial.