Modification of the Innate Immune Response using Low Molecular Weight Substances and its Effect on Different Tumor Types

Abstract

Cancer presents in multifarious forms and remains a paramount contributor to global mortality. Unfortunately, existing local and systemic interventions for diverse neoplasms exhibit suboptimal efficacy. A longstanding acknowledgment endures regarding the immune system’s potential to combat nascent tumors. However, the presence of immunosuppressive factors, as expressed by malignant cells, may obscure the host’s capacity to eradicate established neoplasms, thereby disrupting the equilibrium between regulatory and effector immune constituents. Consequently, concurrent with conventional modalities, immunotherapeutic strategies have flourished in recent years, yielding promising outcomes in the field of oncology. Central to immunotherapy is the innate capacity of the organism to elicit an anti-tumor response through deliberate immunostimulation.