Bacteriophages as an Emerging Alternative and Supplement to Antibiotics, including Prophylaxis to Limit Antibiotic Use

Abstract

The rise of antimicrobial resistance (AMR) has created a critical need for alternatives to traditional antibiotics. Bacteriophages, viruses that specifically target bacteria, are emerging as a potential solution. This literature review examines the use of bacteriophages, both as alternatives and supplements to antibiotics, highlighting their applications, advantages, and challenges. The concept of Phage-Antibiotic Synergy (PAS) is explored, demonstrating how phages can enhance the efficacy of antibiotics under certain conditions.