Embriófelszívódást okozó granulosasejtes petefészek-daganat kancában Esetismertetés

Abstract

SUMMARY Background: Granulosa cell type tumours are the most common tumour in the equine ovary. They are usually benign and unilateral. They are often associated with the cessation of the normal oestrous cycle in mares and the suppression of the normal remaining ovary. Clinical diagnosis of this condition is based on hormone tests (inhibin, testosterone, progesterone) but suspected diagnosis can be made based on physical examination (rectal palpation, ultrasonography, dis section). Objectives: The aim of this study was to summarize the present knowledge about granulosa cell type (GCT) tumours in mares and to present an atypical case from the practice. Materials and methods: A 22-year-old Holstein broodmare has been pre sented with previous pregnancy loss in the history. Therefore a specialized reproductive examination has been performed (physical examination, rectal and ultrasonographic examination, hormone analysis, endometrium biopsy). Based on the owner’s decision, the mare was euthanized and the left ovary has been fixed in buffered formalin solution and histological examination has been made. Results and discussion: Based on all information available, the diagnosis of granulosa cell type tumour has been made. Interestingly, the contralateral ovary was not affected, because the mare could have been pregnant and there were active ovarian structures (follicles and corpora lutea) on the right ovary during the last breeding season. The authors could conclude that in case of GCTs, a thorough reproductive examination in needed for the diagnosis, but in case of this condition, the contralateral ovary is not always affected and mares some times are able to conceiv