A retinás ribbon szinapszisok : Szinaptikus ribbonok a retina patológiás folyamatainak hátterében

Abstract

From the collected data of many years of research it is already known that retinal synaptic ribbons look like electron dense, osmiphilic, plate-like proteinaceous bodies on EM pictures that are surrounded by synaptic vesicles. These specialised synaptic machines are characteristic for the presynaptic temals of cochlear hair cells, pinealocytes and the retinal photorecetors and bipolar neurons. The output synapses of these sensory neurons must provide fast signaling to follow rapidly changing stimuli, while also transmitting graded information covering a wide range of stimulus intensity and sustained for long time periods.