A spermidin hatása az öregedő hippocampusra

Abstract

Due to the recent advance in modern medicine, the average age of the human population has increased significantly, however, learning and cognitive disabilities are common negative factors among symptoms in the aged population. One pivotal factor in the obvious decline in cognitive function during aging is presumed to be the reduced synthesis of endogenous polyamines in the nervous system. The production of spermidine – an aliphatic polyamine – is also being reduced during aging, but its exogenous administration by food seems to be effective in relieving multiple signs of dementia.