Fecal microbiota transplantation and its effect on dogs with chronic enteropathy

Abstract

Dysbiosis refers to an imbalance in the intestinal microbiota composition that can be linked to gastrointestinal dysfunctions. Therapeutic approaches of dysbiosis aim to modulate and support the intestinal microbiome. One of the most promising therapeutic interventions is FMT. FMT involves transferring fecal sample from donor dog into the gastrointestinal tract of a diseased recipient using methods such as oral capsules, endoscopy or rectal enema, with the goal of restoring intestinal barrier integrity. As a new method, FMT currently lacks standardization in veterinary sciences, and requires further research. The aim of our study was to provide better knowledge on FMT-procedure, as well as introduce FMT to the small animal practice and establish a fecal donor program in Hungary.