Browsing by Author "Jerzsele, Ákos"
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Az amoxicillin-klavulánsav kombináció összehasonlító farmakokinetikája brojlercsirkében és pulykában, valamint baktérium-érzékenységi és stabilitási vizsgálata
Jerzsele, Ákos (2009)Az amoxicillin-klavulánsav kombináció széles antibakteriális spektruma, baktericid hatásmódja, valamint nagy terápiás indexe miatt világszerte alkalmazott antibiotikum a humán és az állatgyógyászatban egyaránt. Mind ... -
Antimicrobial Susceptibility Profiles of Pasteurella multocida Isolates from Clinical Cases of Waterfowl in Hungary between 2022 and 2023
Kerek, Ádám; Szabó, Ábel; Jerzsele, Ákos (2024)The waterfowl industry represents a narrow, yet economically significant, sector within the poultry industry. Although less prominent, the waterfowl sector is nonetheless of equal importance to any other livestock sector ... -
Antimikrobiális rezisztencia hazai nagylétszámú házityúk- állományokban, hasznosítási irányok alapján 2022-2023 között
Barnácz, Franciska; Kerek, Ádám; Csirmaz, Bence; Román, István László; Gál, Csaba; Horváth, Áron; Hajduk, Eszter; Szabó, Ábel; Jerzsele, Ákos; Kovács, László (2024-06)Background: Antimicrobial resistance (AMR) represents a significant contemporary challenge, necessitating national action plans complemented by continuous and targeted monitoring efforts. The critical need for such ... -
Antiviral Drug Candidate Repositioning for Streptococcus suis Infection in Non-Tumorigenic Cell Models
Anzet van Niekerk, Ashley; Maluck, Sara; Mag, Patrik; Kővágó, Csaba; Kerek, Ádám; Jerzsele, Ákos; Steinmetzer, Torsten; Pászti-Gere, Erzsébet (2024)The increasing prevalence of antimicrobial resistance against zoonotic bacteria, including Streptococcus (S.) suis, highlights the need for new therapeutical strategies, including the repositioning of drugs. In this study, ... -
Comprehensive Metagenomic Analysis of Veterinary Probiotics in Broiler Chickens
Kerek, Ádám; Román, István László; Szabó, Ábel; Papp, Márton; Bányai, Krisztián; Kardos, Gábor; Kaszab, Eszter; Bali, Krisztina; Makrai, László; Jerzsele, Ákos (2024)Probiotics are widely used in broiler chickens to support the gut microbiome, gut health, and to reduce the amount of antibiotics used. Despite their benefits, there is concern over their ability to carry and spread ... -
Deep Sequencing of Porcine Reproductive and Respiratory Syndrome Virus ORF7: A Promising Tool for Diagnostics and Epidemiologic Surveillance
Jakab, Szilvia; Bali, Krisztina; Freytag, Csongor; Pataki, Anna; Fehér, Enikő; Halas, Máté; Jerzsele, Ákos; Szabó, István; Szarka, Krisztina; Bálint, Ádám; Bányai, Krisztián (2023)Porcine reproductive and respiratory syndrome virus (PRRSV) is a major concern worldwide. Control of PRRSV is a challenging task due to various factors, including the viral diversity and variability. In this study, we ... -
Determining the In Vivo Efficacy of Plant-Based and Probiotic-Based Antibiotic Alternatives against Mixed Infection with Salmonella enterica and Escherichia coli in Domestic Chickens
Kerek, Ádám; Szabó, Ábel; Dobra, Péter Ferenc; Bárdos, Krisztina; Ózsvári, László; Fehérvári, Péter; Bata, Zsófia; Molnár-Nagy, Viviána; Jerzsele, Ákos (2023)Restrictions on the use of antimicrobial compounds have led to a surge of interest in alternative solutions, such as natural, plant-based compounds. In our study, we investigated the efficacy of three feed supplements ... -
Effects of Lactobacillus rhamnosus DSM7133 on Intestinal Porcine Epithelial Cells
Palkovicsné Pézsa, Nikolett; Kovács, Dóra; Somogyi, Fanni; Karancsi, Zita; Móritz, Alma Virág; Jerzsele, Ákos; Rácz, Bence; Farkas, Orsolya (2023)Antimicrobial resistance is one of the biggest health challenges nowadays. Probiotics are promising candidates as feed additives contributing to the health of the gastrointestinal tract. The beneficial effect of probiotics ... -
Egysejtű élősködők ellen alkalmazható gyógyszerek az állatorvoslásban : Irodalmi összefoglaló
Tuska-Szalay, Barbara; Jerzsele, Ákos; Hornok, Sándor (2024-08)Protozoa are unicellular parasites with high veterinary-medical importance, as they can cause mild to severe diseases with multiorgan involvement in pets, livestock and wild-living animals, some of them having zoonotic ... -
Epidemiology and Clinical Manifestation of West Nile Virus Infections of Equines in Hungary, 2007-2020
Fehér, Orsolya Eszter; Fehérvári, Péter; Tolnai, Csenge Hanna; Forgách, Petra; Malik, Péter; Jerzsele, Ákos; Wagenhoffer, Zsombor; Szenci, Otto; Korbacska-Kutasi, Orsolya (2022)West Nile virus (WNV) is an emerging pathogen in Hungary, causing severe outbreaks in equines and humans since 2007. The aim of our study was to provide a comprehensive report on the clinical signs of West Nile neuroinvasive ... -
Farmakokinetikai/farmakodinámiai modellekre alapozott antibakteriális terápia a kisállatgyógyászatban – 1. rész Irodalmi összefoglaló
Mag, Patrik; Németh, Krisztián; Somogyi, Zoltán; Jerzsele, Ákos (2023-07)The antimicrobial resistance (AMR) is one of the most threatening problems of human health. In both public and animal health, multi-drug resistant (MDR) bacterial strains are increasingly emerging, which results in ... -
Gyógynövényekből kivont illóolajok antimikrobiális spektruma – állategészségügyi vonatkozások
Kovács, László; Nagy, Dominika; Könyves, László; Jerzsele, Ákos; Kerek, Ádám (2023-08)The spread of antimicrobial resistance is a growing public and animal health problem worldwide. In animal health industry, especially in livestock management the use of antibiotics for non-therapeutic purposes, mainly as ... -
Immune response to zinc oxide inhalation in metal fume fever, and the possible role of IL-17f
Szűcs-Somlyó, Éva; Lehel, József; Májlinger, Kornél; Tóth, Fruzsina; Jerzsele, Ákos; Kővágó, Csaba (Nature, 2023)Metal fume fever (MFF) is a work-related disease caused by the inhalation of metal particles, including zinc oxide. Chronic asthma may develop as a long-term consequence of exposure, particularly for welders and metal ... -
In Vitro Efficacy of Hungarian Propolis against Bacteria, Yeast, and Trichomonas gallinae Isolated from Pigeons—A Possible Antibiotic Alternative?
Kerek, Ádám; Csanády, Péter; Tuska-Szalay, Barbara; Kovács, László; Jerzsele, Ákos (2023)The spread of antimicrobial resistance is one of the most serious human and animal health problems of our time. Propolis is a natural substance with antibacterial, antifungal, and antiparasitic activity, the most active ... -
In Vitro Microevolution and Co-Selection Assessment of Amoxicillin and Cefotaxime Impact on Escherichia coli Resistance Development
Kerek, Ádám; Török, Bence; Laczkó, Levente; Somogyi, Zoltán; Kardos, Gábor; Bányai, Krisztián; Kaszab, Eszter; Bali, Krisztina; Jerzsele, Ákos (2024)The global spread of antimicrobial resistance has become a prominent issue in both veterinary and public health in the 21st century. The extensive use of amoxicillin, a beta-lactam antibiotic, and consequent resistance ... -
In Vitro Microevolution and Co-Selection Assessment of Florfenicol Impact on Escherichia coli Resistance Development
Kerek, Ádám; Török, Bence; Laczkó, Levente; Kardos, Gábor; Bányai, Krisztián; Somogyi, Zoltán; Kaszab, Eszter; Bali, Krisztina; Jerzsele, Ákos (MDPI, 2023)The issue of antimicrobial resistance is becoming an increasingly serious challenge in both human and veterinary medicine. Prudent antimicrobial use in veterinary medicine is warranted and supported by international ... -
In Vitro Pharmacokinetic Behavior of Antiviral 3-Amidinophenylalanine Derivatives in Rat, Dog and Monkey Hepatocytes
Lányi, Katalin; Monostory, Katalin; Steinmetzer, Torsten; Jerzsele, Ákos; Pászti-Gere, Erzsébet (2023)Type II transmembrane serine proteases represent pharmacological targets for blocking entry and spread of influenza or coronaviruses. In this study, the depletion rates of the 3-amidinophenylalanine (3-APhA)-derived ... -
Kutya bélrendszeri megbetegedéseinek in vitro modellezési lehetőségei - Irodalmi összefoglaló
Móritz, Alma Virág; Jerzsele, Ákos; Psáder, Roland; Farkas, Orsolya (2023-08)The gastrointestinal tract has a large surface area in contact with harmful agents that enter the body through the oral route, and through its complex function, it plays a significant role in keeping pathogenic microorganisms ... -
Luteolin: A Phytochemical to Mitigate S. Typhimurium Flagellin-Induced Inflammation in a Chicken In Vitro Hepatic Model
Tráj, Patrik; Sebők, Csilla; Mackei, Máté; Kemény, Ágnes; Farkas, Orsolya; Kákonyi, Ákos; Kovács, László; Neogrády, Zsuzsanna; Jerzsele, Ákos; Mátis, Gábor (2023)The use of natural feed supplements is an alternative tool to diminish the damage caused by certain bacteria, improving animal health and productivity. The present research aimed to investigate the proinflammatory effect ... -
Monitoring Changes in the Antimicrobial-Resistance Gene Set (ARG) of Raw Milk and Dairy Products in a Cattle Farm, from Production to Consumption
Kerek, Ádám; Németh, Virág; Szabó, Ábel; Papp, Márton; Bányai, Krisztián; Kardos, Gábor; Kaszab, Eszter; Bali, Krisztina; Nagy, Zoltán; Süth, Miklós; Jerzsele, Ákos (2024)Raw milk and dairy products can serve as potential vectors for transmissible bacterial, viral and protozoal diseases, alongside harboring antimicrobial-resistance genes. This study monitors the changes in the antimicrobi ...