dc.description.abstract | Zoonotic foodborne diseases have the potential to infect humans through consumption
of infected animal origin products. The occurrence, infectivity, pathogenicity and overall
risk of these diseases are closely linked to both human and animal health.
Hepatitis E Virus is an RNA virus of the Hepeviridae family. The virus species that
has veterinary public health importance is named Orthohepevirus A and consists of 8
genotypes, all of the same serotype. Hepatitis E is considered an emerging zoonotic
disease, occurring worldwide in a variety of hosts, including, among others, humans,
swine, deer and rabbit/hare.
In humans, the virus can cause both acute and chronic hepatitis, as well as different
extrahepatic manifestations. Large waterborne epidemics are seen in developing
countries, while in the developed world the disease is sporadic, and mainly due to
foodborne infection caused by genotype 3 and 4 viruses.
Among other animal species, wild boars serve as a reservoir for the virus, and can
both spread and infect domesticated pig herds, as well as pose a direct risk of human
infection by the consumption of wild game.
The aims of this study was to investigate and compare the prevalence of HEV
infection and find evidence of the epidemiological connections between wild boar
populations in Austria, Hungary and Serbia. Altogether 482 tissue and sera samples were
collected (48 from Austria, 382 from Hungary and 63 from Serbia). The samples were
subjected to ELISA testing and NA investigations by RT-PCR and qRT-PCR. | en_US |