| dc.description.abstract | Summary
Background: Although non-steroidal anti-inflammatory drugs (NSAID) are increasingly
used to reduce postpartum pain in dystocic cows and calves, the positive effects of
NSAIDs on the well-being of the animals are still not proved.
Objectives: In this study, the effects of a single-dose NSAID-treatment were investi gated on well-being indicators (i.e., heart rate variability and standing time) in new-born
calves (n = 24).
Materials and Methods: The following parameters were investigated within the first 48
hours of life: (1) vitality scores (between 0 and 12) immediately after delivery and 2, and 24
hours thereafter; (2) time spent with standing during the first 2, 6, 12, 24 and 48 hours of
life, respectively; (3) sympathetic and parasympathetic indices of heart rate variability cal culated for lying posture. Calves were allocated into groups as follows: Group 1: low vitality
(between 2 and 7 scores, n= 8); Group 2: low vitality (between scores 2 and 7 + NSAID (single
dose, 5 mg/ml meloxicam, 0,5 mg/kg live body weight, n = 8); Group 3: excellent vitality
(between 10 and 12 scores, n = 8). Calves from Groups 1 and 2 were born from dystocia.
Results and Discussion: Calves with excellent vitality spent more time in standing
than calves in the other groups for all studied periods (p < 0.05 for all comparisons).
Based on lower values of the root mean square of the successive R–R intervals and
the high frequency component of heart rate variability calves from Group 1 exhibited
lower vagal activity either than animals that received NSAID treatment or animals with
excellent vitality following the first 12 hours. It indicates a greater postnatal stress load
in calves with low vitality and suggest that NSAID treatment is successful in reducing
stress/pain after a difficult calving in new-borns. Time spent in standing showed a strong
positive linear correlation with vitality scores for both 2 (r = 0.67, p = 0.012) and 24 hours
after delivery (r = 0.79, p = 0.01). Based on our results, time spent in standing may be an
appropriate indicator of vitality in new-born calves. Single dose of NSAID decreases stress
and pain caused by dystocia and increases time spent with standing in new-born calves
during the first 24 hours of life. | en_US |
