Inherited Diseases and Disorders in Western Horse Breeds

Abstract

A number of single gene mutations have been described in Quarter Horsesand related breeds, which can be observedin the elite performanceand breeding horse industry.Type 1Polysaccharide Storage Myopathy (PSSM), Hyperkalemic Periodic Paralysis (HYPP), Glycogen Branching Enzyme Deficiency (GBED), Malignant Hyperthermia (MH) and Myosin Heavy Chain Myopathy (MYHM)cause various types of muscle diseases,whereasthe specific clinical signs depend on the individual signal pathway.