| dc.description.abstract | D-dimer is a soluble fibrin degradation product originating from the plasmin-mediated
degradation of cross-linked fibrin. Thus, D-dimer is thought of to be a biomarker for the
activation of coagulation and fibrinolysis and is used as an ancillary method to rule out
diseases such as thromboembolic disease and other haemostatic disorders. D-dimer levels
may rise for a variety of reasons; it is not a disease-specific condition. As a result, a precise
diagnosis cannot be established solely on the basis of an increase in D-dimer levels. The
main objective of this thesis is to revise the meaning of D-dimer, compare D-dimer assays,
discuss its relation to diseases, and its use in clinical settings and their critical investigation. | en_US |
