| dc.description.abstract | Background: Antimicrobial resistance (AMR) represents a significant contemporary
challenge, necessitating national action plans complemented by continuous and
targeted monitoring efforts. The critical need for such monitoring is especially pro-
nounced for pathogens that pose a substantial risk to both animal and public health,
within varied geographical contexts.
Objectives: This study aimed to evaluate the susceptibility of key pathogenic bacteria
— Staphylococcus, Enterococcus and Escherichia coli — to essential antimicrobial agents.
These bacteria were selected due to their significant impact on animal health and
their potential threat to public health, underscoring the importance of understanding
their resistance patterns in large domestic flocks.
Materials and Methods: In several predefined regions in Hungary, we collected
fifteen tracheal and fifteen cloacal swab samples from at least three sites per region.
This extensive sampling facilitated the isolation of bacterial strains, whose sensitivity
was subsequently assessed through minimum inhibitory concentration (MIC) deter-
mination. The resultant data were then analyzed to discern any significant variances
in resistance patterns in different types of livestock utilization.
Results and Discussion: Our findings revealed marked differences in AMR profiles,
particularly between meat-producing herds and others. Notably, vancomycin resistance
of Staphylococcus from breeding herds reached 19.7%, highlighting a potential health
crisis. Resistance to amoxicillin and neomycin was generally low, under 20%. Entero-
coccus showed a drastic 91.6% resistance to spectinomycin in meat flocks, contrasted
with 23.3% in breeding flocks. Sulphonamide resistance was significantly varied, peak-
ing in breeding flocks at 83.6%. Escherichia coli resistance to several antibiotics was
significantly higher in meat herds than in breeding herds, underscoring the need for
targeted interventions. The pronounced AMR variances in different types of livestock
underline the necessity for tailored surveillance and interventions. Our study sheds
light on the AMR scenario within Hungary's agricultural sector, offering insights for
developing more nuanced AMR management and control strategies. | en_US |
