Modification of the Innate Immune Response using Low Molecular Weight Substances and its Effect on Different Tumor Types
Abstract
Cancer presents in multifarious forms and remains a paramount contributor to global
mortality. Unfortunately, existing local and systemic interventions for diverse neoplasms exhibit
suboptimal efficacy. A longstanding acknowledgment endures regarding the immune system’s
potential to combat nascent tumors. However, the presence of immunosuppressive factors, as
expressed by malignant cells, may obscure the host’s capacity to eradicate established
neoplasms, thereby disrupting the equilibrium between regulatory and effector immune
constituents. Consequently, concurrent with conventional modalities, immunotherapeutic
strategies have flourished in recent years, yielding promising outcomes in the field of oncology.
Central to immunotherapy is the innate capacity of the organism to elicit an anti-tumor
response through deliberate immunostimulation.