| dc.description.abstract | Heartworm disease, caused by Dirofilaria immitis, is an increasingly prevalent illness in
canines that can lead to severe complications if left untreated. Transmitted by mosquitoes, it
is a globally disseminated disease, particularly common in Europe, Asia, Australia, and
North America. The objective of this review is to provide an overview of heartworm disease
and emphasize the significance of Macrocyclic lactones in heartworm prophylaxis.
Additionally, current findings on resistance, dosing strategies, and side effects are
summarized. Macrocyclic lactones, which are the primary agents for heartworm prevention,
are classified into two groups: avermectin and milbemycin. | en_US |
