A comparative study of different pain management protocols in the perioperative period on cranial cruciate ligament ruptured dogs which undergo TPLO surgery

Abstract

The successfulness, based on the antinociceptive efficacy, opioid and Isoflurane sparing properties and the consideration of adverse side effects, of a Fentanyl-Ketamine continuous rate infusion (CRI) and certain local anesthesia techniques as add-ons to the ordinary perioperative analgesic drug protocol was examined in the prospective study described in the following. Therefore, 60 dogs which were scheduled for Tibial Plateau Leveling Osteotomy (TPLO), according to a group sequential design, were randomly selected for one of the four study protocols.