| dc.description.abstract | Nowadays, as a result of the abundant and inappropriate use of antibiotics, resistance in
bacteria against these agents poses a potentially great risk in both veterinary and human
medicine. The increasing prevalence of resistant strains can lead to treatment failure,
which is especially important in case of infections caused by zoonotic bacteria such as
Escherichia coli and Salmonella enterica ser. Typhimurium. This phenomenon can only
be overcome with the ‘One Health’ concept, where the veterinary and human fields work
together in finding solutions to decrease and optimise the usage of antibiotics and to find
potential antibiotic alternatives that can help in the prevention and treatment of bacterial
infections. Among many natural substances, flavonoids, including proanthocyanidins
(PACs), might be used for this purpose due to their antioxidant, anti-inflammatory and
antibacterial properties. | en_US |
