National Laboratory of Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety
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The establishment of the National Laboratory (NL) of Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety is of particular importance from the point of view of public health and national economy. The large number of farm animals in our country, as well as the year-by-year increase in income from this, make the rapid and effective detection, prevention and treatment of infectious diseases an important priority. In the spirit of the One Health principle, the health protection of those who consume animal products is extremely important, in the development of which NL also plays a role. As the only veterinary training institution in Hungary, ÁTE plays a key role in ensuring the supply of researchers and teachers. The recognition, prevention and treatment of infectious animal diseases will be even more important in the future than before, with the growing national economic importance of the sector and the growing demand for high-quality animal products. In order to achieve the above goal, NL provides research-development-innovation as well as practice-oriented higher education capacity, so it is maximally compatible with component B of Hungary’s Recovery and Resilience Plan (highly qualified, competitive workforce). In addition to the fact that our main goal is to set up a NL that works closely with industrial partners and other partner institutions in the long term, by the end of the project period we plan to market several products and services that are partially unique and innovative and partially fill gaps in the domestic context. Depending on their nature, we publish our research results in the form of protection/patent, or we plan to publish them in prestigious, international journals in a freely accessible format and make them available to society.
Recent Submissions
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First Broad-Range Serological Survey of Crimean-Congo Hemorrhagic Fever among Hungarian Livestock
(2024)(1) Background: Crimean-Congo hemorrhagic fever (CCHF) is an emerging tick-borne disease endemic in Africa, Asia, the Middle East, and the Balkan and Mediterranean regions of Europe. Although no human CCHF cases have been ... -
Epidemiology and Clinical Manifestation of West Nile Virus Infections of Equines in Hungary, 2007-2020
(2022)West Nile virus (WNV) is an emerging pathogen in Hungary, causing severe outbreaks in equines and humans since 2007. The aim of our study was to provide a comprehensive report on the clinical signs of West Nile neuroinvasive ... -
Monitoring Changes in the Antimicrobial-Resistance Gene Set (ARG) of Raw Milk and Dairy Products in a Cattle Farm, from Production to Consumption
(2024)Raw milk and dairy products can serve as potential vectors for transmissible bacterial, viral and protozoal diseases, alongside harboring antimicrobial-resistance genes. This study monitors the changes in the antimicrobi ... -
Antimicrobial Susceptibility Profiles of Pasteurella multocida Isolates from Clinical Cases of Waterfowl in Hungary between 2022 and 2023
(2024)The waterfowl industry represents a narrow, yet economically significant, sector within the poultry industry. Although less prominent, the waterfowl sector is nonetheless of equal importance to any other livestock sector ... -
Structural similarity of human papillomavirus E4 and polyomaviral VP4 exhibited by genomic analysis of the common kestrel (Falco tinnunculus) polyomavirus
(2024)Polyomaviruses are widely distributed viruses of birds that may induce developmental deformities and internal organ disorders primarily in nestlings. In this study, polyomavirus sequence was detected in kidney and liver ... -
A CTB-SARS-CoV-2-ACE-2 RBD Mucosal Vaccine Protects Against Coronavirus Infection
(2023)Mucosal vaccines protect against respiratory virus infection by stimulating the production of IgA antibodies that protect against virus invasion of the mucosal epithelium. In this study, a novel protein subunit mucosal ... -
Evaluation of the Virulence of Low Pathogenic H9N2 Avian Influenza Virus Strains in Broiler Chickens
(2023)Our study aimed to investigate the virulence of three recent H9N2 LPAIV strains belonging to the G1 lineage, isolated from field infections in North Africa and the Middle East. Three-week-old commercial broiler chickens ... -
Determining the In Vivo Efficacy of Plant-Based and Probiotic-Based Antibiotic Alternatives against Mixed Infection with Salmonella enterica and Escherichia coli in Domestic Chickens
(2023)Restrictions on the use of antimicrobial compounds have led to a surge of interest in alternative solutions, such as natural, plant-based compounds. In our study, we investigated the efficacy of three feed supplements ... -
Carry-Over of Aflatoxin B1 from Feed to Cow Milk-A Review
(2023)The conversion of aflatoxin B1 in feed consumed by cows into aflatoxin M1 in their milk poses a challenge to food safety, with milk being a popular staple food and because of the harmful effects of these compounds. This ... -
Investigation of the effects of T-2 toxin in chicken-derived three-dimensional hepatic cell cultures
(2024)Despite being one of the most common contaminants of poultry feed, the molecular effects of T-2 toxin on the liver of the exposed animals are still not fully elucidated. To gain more accurate understanding, the effects of ... -
In Vitro Efficacy of Hungarian Propolis against Bacteria, Yeast, and Trichomonas gallinae Isolated from Pigeons—A Possible Antibiotic Alternative?
(2023)The spread of antimicrobial resistance is one of the most serious human and animal health problems of our time. Propolis is a natural substance with antibacterial, antifungal, and antiparasitic activity, the most active ... -
Pap12-6: A host defense peptide with potent immunomodulatory activity in a chicken hepatic cell culture
(2024)In the fight against antimicrobial resistance, host defense peptides (HDPs) are increasingly referred to as promising molecules for the design of new antimicrobial agents. In terms of their future clinical use, particularly ... -
Label-Free Detection of African Swine Fever and Classical Swine Fever in the Point-of-Care Setting Using Photonic Integrated Circuits Integrated in a Microfluidic Device
(2024)Swine viral diseases have the capacity to cause significant losses and affect the sector's sustainability, a situation further exacerbated by the lack of antiviral drugs and the limited availability of effective vaccines. ... -
Genomic epidemiology of antifungal resistance in human and avian isolates of Candida albicans: a pilot study from the One Health perspective
(2024)Stress-induced genomic changes in Candida albicans contribute to the adaptation of this species to various environmental conditions. Variations of the genome composition of animal-origin C. albicans strains are largely ... -
Genome stability assessment of PRRS vaccine strain with new ARTIC-style sequencing protocol
(2024)A tiling amplicon sequencing protocol was developed to analyse the genome sequence stability of the modified live PRRSV vaccine strain, Porcilis MLV. The backbone of the ARTIC-style protocol was formed by 34 individual ... -
Novel parvovirus in an outbreak of fatal enteritis in European hedgehogs (Erinaceus europaeus), Italy, 2022
(2023)Starting from June 2022, increased mortality associated with enteric signs was reported in European hedgehogs (Erinaceus europaeus) recovered at a regional wildlife rescue center, in Apulia, Italy. Cases of enteric disease ... -
Detrimental consequences of tebuconazole on redox homeostasis and fatty acid profile of honeybee brain
(2023)Excessive use of azole fungicides in agriculture poses a potential threat to honeybees and other pollinator insects; however, the detailed effects of these molecules remain largely unclear. Hence, in the present study it ... -
Genetic diversity of imported PRRSV-2 strains, 2005-2020, Hungary
(2022)Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2) remains sporadic in Europe. In this study, we investigated the molecular epidemiology of PRRSV-2 infections encompassing 15 years in Hungary. Partial (423 bp ... -
Phenotypic and genetic insights into efflux pump mechanism in Mycoplasma anserisalpingitidis
(2023)Introduction Mycoplasma anserisalpingitidis is one of the most important waterfowl-pathogenic mycoplasmas. Due to inadequate antibiotic treatment, many strains with high minimal inhibitory concentration (MIC) values for ... -
Establishment of a Mycoplasma hyorhinis challenge model in 5-week-old piglets
(2023)Introduction: Mycoplasma hyorhinis is an emerging swine pathogen with high prevalence worldwide. The main lesions caused are arthritis and polyserositis, and the clinical manifestation of the disease may result in significant ...