A lenmagolajjal végzett takarmánykiegészítés hatása a gnotobiotikus malacok lipidanyagcseréjére

Abstract

SUMMARY The authors examined the effect of the application of flax-seed oil rich in omega-3 polyunsaturated fatty acids on the lipid metabolism in gnotobiotic pigs inoculated with probiotic lactobacilli. Germ-free piglets were obtained via open hysterotomy and divided into 2 groups – experimental and control. All animals were inoculated from the 1st day of life with probiotic strain of Lactobacillus plantarum – Biocenol™ LP96. The diet of piglets in the experimental group was supplemented with flax-seed oil with high content of omega-3 PUFA and control piglets received the same amount of sunflower oil containing only omega-6 PUFA. The results showed significant influence of flax-seed oil on lipid metabolism parameters. Concentration of triacylglycerols was lower after the administration of flax-seed oil, the levels of total cholesterol were similar in both groups, but levels of HDL cholesterol were higher, while levels of LDL cholesterol were lower in experimental animals. The addition of flax-seed caused significant increase in proportion of eicosapentaenoic and docosahexaenoic acids in serum lipids at the expense of arachidonic acid, the concentration of which decreased significantly. We also noted an increase in the level of short chain fatty acids in experimental piglets compared to the control animals. Flax-seed oil seems to be a suitable source of omega-3 PUFA, but healthy gut microbiota is necessary for maximal effect of such supplementation.